Saccharinsodium 99% supplier GMP CAS NO.128-44-9

1.USP/EP/BP/FCC/CP 2.GMP/DMF/KOSHER/HALAL/HACCP 3.10 Years Experience 4.Delivery within 5 days 5.OEM ability …

1.USP/EP/BP/FCC/CP
2.GMP/DMF/KOSHER/HALAL/HACCP
3.10 Years Experience
4.Delivery within 5 days
5.OEM ability

1.Introduction of Sodium saccharin

Sodium saccharin is the salt form of saccharin, an artificial sweetener. Like many other salts, it dissociates into its component parts when dissolved in water. The words "sodium saccharin" and "saccharin" are used interchangeably because saccharin is the component that has the sweet taste. Both names are easier to use than the true chemical name, which is 1,2-benzisothiazol-3(2H)-one,1,1-dioxide. This chemical has a molecular weight of 241.19. Sodium saccharin has 300 times the sweetening power of sugar. Inert bulking agents are commonly added to commercial products to make them easier to use.

2.Properties of Sodium saccharin

(1)ACD/LogP: 0.464   (2)# of Rule of 5 Violations: 0                     
(3)ACD/LogD (pH 5.5): -2.98   (4)ACD/LogD (pH 7.4): -3.04
(5)ACD/BCF (pH 5.5): 1.00   (6)ACD/BCF (pH 7.4): 1.00
(7)ACD/KOC (pH 5.5): 1.00   (8)ACD/KOC (pH 7.4): 1.00
(9)#H bond acceptors: 4   (10)#H bond donors: 1
(11)#Freely Rotating Bonds: 0   (12)Polar Surface Area: 75.11 ?2 
(13) Polarizability: 10-24cm3 (14)Flash Point: 219.3 °C

(15)Enthalpy of Vaporization: 73.34 kJ/mol
(16)Boiling Point: 438.9 °C at 760 mmHg (17)Vapour Pressure: 1.77E-08 mmHg at 25°C

3.Structure Descriptors of Sodium saccharin

SMILES:[Na+].[O-]/C2=N/S(=O)(=O)c1ccccc12

Std. InChI: InChI=1S/C7H5NO3S.Na/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;/h1-4H,(H,8,9);/q;+1/p-1

Std. InChIKey: WINXNKPZLFISPD-UHFFFAOYSA-M

4.Uses of Sodium saccharin

In addition to the little packets found in dishes on restaurant table tops, sodium saccharin is customarily used in canned fruit, flavored gelatin, dessert toppings, diet sodas, baked goods, jams, chewing gum, candy, and salad dressings. Unlike aspartame, sodium saccharin is heat stable so it can be used in cooking and baking without losing sweetness.

5.Toxicological Information

RTECS#:
CAS# 128-44-9: DE4550000
LD50/LC50:
CAS# 128-44-9:
Oral, mouse: LD50 = 17500 mg/kg;
Oral, rat: LD50 = 14200 mg/kg;
.

Carcinogenicity:

CAS# 128-44-9: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: Several studies in rats & mice have linked sodium saccharin to bladder tumors, but the mechanism believed to induce cancer in those animals does not appear to occur in humans.

Teratogenicity: No data available.

Reproductive Effects: See actual entry in RTECS for complete information.

Mutagenicity: See actual entry in RTECS for complete information.

Neurotoxicity: No data available

6.Safety Information of Sodium saccharin

Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.

 
Ingestion: Get medical aid if irritation or symptoms occur.

Inhalation: Remove from exposure and move to fresh air immediately. Get medical aid if cough or other symptoms appear.

Notes to Physician: Treat symptomatically and supportively.

7. Delivery information

Delivery within 5 days